Preclinical Data Readout for MDL-001 - Direct-Acting, Broad-Spectrum Antiviral

Get in Touch

Get in Touch

Preclinical Data Readout for MDL-001 - Direct-Acting, Broad-Spectrum Antiviral

Preclinical Data Readout for MDL-001 - Direct-Acting, Broad-Spectrum Antiviral

Get in Touch

Get in Touch

Newsroom

Newsroom

Newsroom

Latest Learnings

Get the latest insights, news, and expert articles from Model Medicines.

LAtest News

Oct 16, 2025

Events

MDL-001 as a Next-Generation HCV Thumb-1 Inhibitor with Clinical-Stage Safety

Oct 16, 2025

Events

MDL-001 as a Next-Generation HCV Thumb-1 Inhibitor with Clinical-Stage Safety

Oct 16, 2025

Events

MDL-001 as a Next-Generation HCV Thumb-1 Inhibitor with Clinical-Stage Safety

Oct 16, 2025

Announcement

Model Medicines To Present Preclinical Data Readout for MDL-001, a Direct-Acting, Broad-Spectrum Antiviral Targeting a Novel Viral Mechanism, at IDWeek™ 2025

Oct 16, 2025

Announcement

Model Medicines To Present Preclinical Data Readout for MDL-001, a Direct-Acting, Broad-Spectrum Antiviral Targeting a Novel Viral Mechanism, at IDWeek™ 2025

Oct 16, 2025

Announcement

Model Medicines To Present Preclinical Data Readout for MDL-001, a Direct-Acting, Broad-Spectrum Antiviral Targeting a Novel Viral Mechanism, at IDWeek™ 2025

Aug 25, 2025

Events

Model Medicines Selected to Present at BARDA's Enabling Technologies Showcase

Aug 25, 2025

Events

Model Medicines Selected to Present at BARDA's Enabling Technologies Showcase

Aug 25, 2025

Events

Model Medicines Selected to Present at BARDA's Enabling Technologies Showcase

Aug 14, 2025

MDL-001

Coronaviruses: Foundations of Broad-Spectrum Series

Aug 14, 2025

MDL-001

Coronaviruses: Foundations of Broad-Spectrum Series

Aug 14, 2025

MDL-001

Coronaviruses: Foundations of Broad-Spectrum Series

Aug 13, 2025

MDL-001

The Foundations of Broad-Spectrum Series

Aug 13, 2025

MDL-001

The Foundations of Broad-Spectrum Series

Aug 13, 2025

MDL-001

The Foundations of Broad-Spectrum Series

Aug 12, 2025

Announcement

Model Medicines to Present Preclinical Proof-of-Concept Data for Broad-Spectrum Antiviral MDL-001 at ID Week 2025

Aug 12, 2025

Announcement

Model Medicines to Present Preclinical Proof-of-Concept Data for Broad-Spectrum Antiviral MDL-001 at ID Week 2025

Aug 12, 2025

Announcement

Model Medicines to Present Preclinical Proof-of-Concept Data for Broad-Spectrum Antiviral MDL-001 at ID Week 2025

Jun 13, 2025

Announcement

Model Medicines Selected for BARDA VANGUARD: Building the Future of U.S. Health Security

Jun 13, 2025

Announcement

Model Medicines Selected for BARDA VANGUARD: Building the Future of U.S. Health Security

Jun 13, 2025

Announcement

Model Medicines Selected for BARDA VANGUARD: Building the Future of U.S. Health Security

Jun 13, 2025

Announcement

Model Medicines Named to Fierce 15

Jun 13, 2025

Announcement

Model Medicines Named to Fierce 15

Jun 13, 2025

Announcement

Model Medicines Named to Fierce 15

Jun 12, 2025

Announcement

Model Medicines Selected for BARDA VANGUARD Program, Strengthening U.S. National Defense Against Biological Threats

Jun 12, 2025

Announcement

Model Medicines Selected for BARDA VANGUARD Program, Strengthening U.S. National Defense Against Biological Threats

Jun 12, 2025

Announcement

Model Medicines Selected for BARDA VANGUARD Program, Strengthening U.S. National Defense Against Biological Threats

Apr 2, 2025

Announcement

Model Medicines Advances AI-Driven Drug Safety Prediction with AmesNet™, Achieving Unprecedented Accuracy and Sensitivity in Mutagenicity Testing

Apr 2, 2025

Announcement

Model Medicines Advances AI-Driven Drug Safety Prediction with AmesNet™, Achieving Unprecedented Accuracy and Sensitivity in Mutagenicity Testing

Apr 2, 2025

Announcement

Model Medicines Advances AI-Driven Drug Safety Prediction with AmesNet™, Achieving Unprecedented Accuracy and Sensitivity in Mutagenicity Testing

Apr 1, 2025

Press

Model Medicines Featured on Bloomberg’s Vanguards of Health Care: Transforming Drug Discovery with AI

Apr 1, 2025

Press

Model Medicines Featured on Bloomberg’s Vanguards of Health Care: Transforming Drug Discovery with AI

Apr 1, 2025

Press

Model Medicines Featured on Bloomberg’s Vanguards of Health Care: Transforming Drug Discovery with AI

Apr 1, 2025

Events

Model Medicines CEO Daniel Haders II to Speak at Bloomberg's 4th Annual Generative AI Conference

Apr 1, 2025

Events

Model Medicines CEO Daniel Haders II to Speak at Bloomberg's 4th Annual Generative AI Conference

Apr 1, 2025

Events

Model Medicines CEO Daniel Haders II to Speak at Bloomberg's 4th Annual Generative AI Conference

Mar 20, 2025

Preprint

AmesNet: A Deep Learning Model Enhancing Generalization in Ames Mutagenicity Prediction

Mar 20, 2025

Preprint

AmesNet: A Deep Learning Model Enhancing Generalization in Ames Mutagenicity Prediction

Mar 20, 2025

Preprint

AmesNet: A Deep Learning Model Enhancing Generalization in Ames Mutagenicity Prediction

Mar 18, 2025

Insights

Antivirals: From One Too Many to One-to-Many

Mar 18, 2025

Insights

Antivirals: From One Too Many to One-to-Many

Mar 18, 2025

Insights

Antivirals: From One Too Many to One-to-Many

Mar 11, 2025

Insights

Biotech’s Undead: Zombies and Vampires

Mar 11, 2025

Insights

Biotech’s Undead: Zombies and Vampires

Mar 11, 2025

Insights

Biotech’s Undead: Zombies and Vampires

Mar 4, 2025

Insights

Transforming Pandemic Preparedness: AI-Driven Predictive Tools and Next-Generation Broad-Spectrum Antivirals

Mar 4, 2025

Insights

Transforming Pandemic Preparedness: AI-Driven Predictive Tools and Next-Generation Broad-Spectrum Antivirals

Mar 4, 2025

Insights

Transforming Pandemic Preparedness: AI-Driven Predictive Tools and Next-Generation Broad-Spectrum Antivirals

Feb 25, 2025

Insights

The Future of Drug Discovery: 2025 as the Inflection Year for Hybrid AI and Quantum Computing

Feb 25, 2025

Insights

The Future of Drug Discovery: 2025 as the Inflection Year for Hybrid AI and Quantum Computing

Feb 25, 2025

Insights

The Future of Drug Discovery: 2025 as the Inflection Year for Hybrid AI and Quantum Computing

Feb 19, 2025

Insights

The STAT News Report: A Wake-Up Call for AI Drug Discovery

Feb 19, 2025

Insights

The STAT News Report: A Wake-Up Call for AI Drug Discovery

Feb 19, 2025

Insights

The STAT News Report: A Wake-Up Call for AI Drug Discovery

Feb 4, 2025

Events

Model Medicines Gains Industry Recognition for AI-Driven Antiviral Breakthroughs 

Feb 4, 2025

Events

Model Medicines Gains Industry Recognition for AI-Driven Antiviral Breakthroughs 

Feb 4, 2025

Events

Model Medicines Gains Industry Recognition for AI-Driven Antiviral Breakthroughs 

Jan 28, 2025

Announcement

Model Medicines Unveils Generative AI, Multi-Modal Therapeutic Pipeline Breakthrough, Demonstrating End-To-End Drug Discovery Capabilities

Jan 28, 2025

Announcement

Model Medicines Unveils Generative AI, Multi-Modal Therapeutic Pipeline Breakthrough, Demonstrating End-To-End Drug Discovery Capabilities

Jan 28, 2025

Announcement

Model Medicines Unveils Generative AI, Multi-Modal Therapeutic Pipeline Breakthrough, Demonstrating End-To-End Drug Discovery Capabilities

Jan 27, 2025

Press

Model Medicines Named Among Top AI Drug Development Startups to Watch in 2025

Jan 27, 2025

Press

Model Medicines Named Among Top AI Drug Development Startups to Watch in 2025

Jan 27, 2025

Press

Model Medicines Named Among Top AI Drug Development Startups to Watch in 2025

Jan 26, 2025

Preprint

Demonstrating End-to-End Drug Discovery: GALILEO™ Unlocks Generative AI for Chemistry

Jan 26, 2025

Preprint

Demonstrating End-to-End Drug Discovery: GALILEO™ Unlocks Generative AI for Chemistry

Jan 26, 2025

Preprint

Demonstrating End-to-End Drug Discovery: GALILEO™ Unlocks Generative AI for Chemistry

Jan 21, 2025

Announcement

Model Medicines, Icahn School of Medicine at Mount Sinai, and University of California, San Diego Researchers Publish Groundbreaking Preprint on MDL-001, A Broad-Spectrum Antiviral

Jan 21, 2025

Announcement

Model Medicines, Icahn School of Medicine at Mount Sinai, and University of California, San Diego Researchers Publish Groundbreaking Preprint on MDL-001, A Broad-Spectrum Antiviral

Jan 21, 2025

Announcement

Model Medicines, Icahn School of Medicine at Mount Sinai, and University of California, San Diego Researchers Publish Groundbreaking Preprint on MDL-001, A Broad-Spectrum Antiviral

Jan 14, 2025

Preprint

MDL-001: An Oral, Safe, and Well-Tolerated Broad-Spectrum Inhibitor of Viral Polymerases

Jan 14, 2025

Preprint

MDL-001: An Oral, Safe, and Well-Tolerated Broad-Spectrum Inhibitor of Viral Polymerases

Jan 14, 2025

Preprint

MDL-001: An Oral, Safe, and Well-Tolerated Broad-Spectrum Inhibitor of Viral Polymerases

Dec 3, 2024

Events

Model Medicines to Keynote CPHI Middle East

Dec 3, 2024

Events

Model Medicines to Keynote CPHI Middle East

Dec 3, 2024

Events

Model Medicines to Keynote CPHI Middle East

Nov 29, 2024

Press

Model Medicines Makes GEN's List of Top AI Drug Discovery Companies to Watch

Nov 29, 2024

Press

Model Medicines Makes GEN's List of Top AI Drug Discovery Companies to Watch

Nov 29, 2024

Press

Model Medicines Makes GEN's List of Top AI Drug Discovery Companies to Watch

Sep 10, 2024

Paper

AI Hit Rates and Novelty

Sep 10, 2024

Paper

AI Hit Rates and Novelty

Sep 10, 2024

Paper

AI Hit Rates and Novelty

A Guide to Streamlining Your Business

Jun 5, 2024

Announcement

Model Medicines Announces Nomination of Preclinical Candidate, MDL-4101, Targeting BRD4 for the Treatment of Thyroid Cancer

A Guide to Streamlining Your Business

Jun 5, 2024

Announcement

Model Medicines Announces Nomination of Preclinical Candidate, MDL-4101, Targeting BRD4 for the Treatment of Thyroid Cancer

A Guide to Streamlining Your Business

Jun 5, 2024

Announcement

Model Medicines Announces Nomination of Preclinical Candidate, MDL-4101, Targeting BRD4 for the Treatment of Thyroid Cancer

Apr 24, 2024

Announcement

Model Medicines Appoints Dr. Launa Aspeslet as Senior Scientific & Clinical Advisor

Apr 24, 2024

Announcement

Model Medicines Appoints Dr. Launa Aspeslet as Senior Scientific & Clinical Advisor

Apr 24, 2024

Announcement

Model Medicines Appoints Dr. Launa Aspeslet as Senior Scientific & Clinical Advisor

Apr 23, 2024

Insights

The AIDD Code

Apr 23, 2024

Insights

The AIDD Code

Apr 23, 2024

Insights

The AIDD Code

Apr 17, 2024

Events

Model Medicines to Participate in Upcoming TSX Investor Event

Apr 17, 2024

Events

Model Medicines to Participate in Upcoming TSX Investor Event

Apr 17, 2024

Events

Model Medicines to Participate in Upcoming TSX Investor Event

Apr 9, 2024

Announcement

Model Medicines Unveils Groundbreaking AI Drug Discovery Advances in New Chemistry and New Biology with Two New Preprint Papers

Apr 9, 2024

Announcement

Model Medicines Unveils Groundbreaking AI Drug Discovery Advances in New Chemistry and New Biology with Two New Preprint Papers

Apr 9, 2024

Announcement

Model Medicines Unveils Groundbreaking AI Drug Discovery Advances in New Chemistry and New Biology with Two New Preprint Papers

Apr 8, 2024

Preprint

Model Medicines Reveals Breakthrough AI Discovery: RdRp Thumb-1, A Universal RNA Antiviral Target, and MDL-001, a Potent Inhibitor

Apr 8, 2024

Preprint

Model Medicines Reveals Breakthrough AI Discovery: RdRp Thumb-1, A Universal RNA Antiviral Target, and MDL-001, a Potent Inhibitor

Apr 8, 2024

Preprint

Model Medicines Reveals Breakthrough AI Discovery: RdRp Thumb-1, A Universal RNA Antiviral Target, and MDL-001, a Potent Inhibitor

Mar 28, 2024

Preprint

Model Medicines Publishes Groundbreaking Preprint on AI-Driven Drug Discovery

Mar 28, 2024

Preprint

Model Medicines Publishes Groundbreaking Preprint on AI-Driven Drug Discovery

Mar 28, 2024

Preprint

Model Medicines Publishes Groundbreaking Preprint on AI-Driven Drug Discovery

Maximizing Your Business Potential

Mar 20, 2024

Announcement

Model Medicines Discovers New Pan-Antiviral Chemical Entity (NCE) Library, Achieving Unprecedented 66.7% Hit Rate Using Proprietary AI Platform

Maximizing Your Business Potential

Mar 20, 2024

Announcement

Model Medicines Discovers New Pan-Antiviral Chemical Entity (NCE) Library, Achieving Unprecedented 66.7% Hit Rate Using Proprietary AI Platform

Maximizing Your Business Potential

Mar 20, 2024

Announcement

Model Medicines Discovers New Pan-Antiviral Chemical Entity (NCE) Library, Achieving Unprecedented 66.7% Hit Rate Using Proprietary AI Platform

Mar 11, 2024

Events

20th BioPharma Drug Discovery Nexus Conference

Mar 11, 2024

Events

20th BioPharma Drug Discovery Nexus Conference

Mar 11, 2024

Events

20th BioPharma Drug Discovery Nexus Conference

Mar 11, 2024

Paper

Dissimilar, Drug-Like, Novel Chemical Entities (DDL-NCEs); Using Multimodal Generative AI

Mar 11, 2024

Paper

Dissimilar, Drug-Like, Novel Chemical Entities (DDL-NCEs); Using Multimodal Generative AI

Mar 11, 2024

Paper

Dissimilar, Drug-Like, Novel Chemical Entities (DDL-NCEs); Using Multimodal Generative AI

Dec 19, 2023

Paper

Biochemistry's Hidden Matrix: Atomic Constellations

Dec 19, 2023

Paper

Biochemistry's Hidden Matrix: Atomic Constellations

Dec 19, 2023

Paper

Biochemistry's Hidden Matrix: Atomic Constellations

Nov 13, 2023

Events

Advancing Preparedness Through BARDA Industry Day

Nov 13, 2023

Events

Advancing Preparedness Through BARDA Industry Day

Nov 13, 2023

Events

Advancing Preparedness Through BARDA Industry Day

Nov 9, 2023

Events

JPM CBRN Medical TechWatch

Nov 9, 2023

Events

JPM CBRN Medical TechWatch

Nov 9, 2023

Events

JPM CBRN Medical TechWatch

Oct 12, 2023

Events

Precision in Drug Discovery & Preclinical Summit 2023

Oct 12, 2023

Events

Precision in Drug Discovery & Preclinical Summit 2023

Oct 12, 2023

Events

Precision in Drug Discovery & Preclinical Summit 2023

Sep 27, 2023

Paper

Vanity Metrics & Black Boxes ≠Therapeutics

Sep 27, 2023

Paper

Vanity Metrics & Black Boxes ≠Therapeutics

Sep 27, 2023

Paper

Vanity Metrics & Black Boxes ≠Therapeutics

Sep 14, 2023

Events

BARDA - TechWatch Meeting

Sep 14, 2023

Events

BARDA - TechWatch Meeting

Sep 14, 2023

Events

BARDA - TechWatch Meeting

Sep 12, 2023

Paper

Breaking the Data Dogma

Sep 12, 2023

Paper

Breaking the Data Dogma

Sep 12, 2023

Paper

Breaking the Data Dogma

May 3, 2023

Events

TiEcon 2023

May 3, 2023

Events

TiEcon 2023

May 3, 2023

Events

TiEcon 2023

Apr 27, 2023

Events

Model Medicines Download Day

Apr 27, 2023

Events

Model Medicines Download Day

Apr 27, 2023

Events

Model Medicines Download Day

Mar 20, 2023

Paper

Overcoming PAINS in AI Drug Discovery

Mar 20, 2023

Paper

Overcoming PAINS in AI Drug Discovery

Mar 20, 2023

Paper

Overcoming PAINS in AI Drug Discovery

Feb 13, 2023

Events

Cryo-EM at the Forefront of AI Drug Discovery: Exploring Deep Chemical Space

Feb 13, 2023

Events

Cryo-EM at the Forefront of AI Drug Discovery: Exploring Deep Chemical Space

Feb 13, 2023

Events

Cryo-EM at the Forefront of AI Drug Discovery: Exploring Deep Chemical Space

Dec 13, 2022

Paper

The Tripledemic: AI-Drug Discovery and the Quest for a Pan-Antiviral Drug

Dec 13, 2022

Paper

The Tripledemic: AI-Drug Discovery and the Quest for a Pan-Antiviral Drug

Dec 13, 2022

Paper

The Tripledemic: AI-Drug Discovery and the Quest for a Pan-Antiviral Drug

Nov 15, 2022

Events

Model Medicines Selected to Participate at the 5th Annual Evercore ISI HealthCONx Conference

Nov 15, 2022

Events

Model Medicines Selected to Participate at the 5th Annual Evercore ISI HealthCONx Conference

Nov 15, 2022

Events

Model Medicines Selected to Participate at the 5th Annual Evercore ISI HealthCONx Conference

Oct 4, 2022

Events

Model Medicines Selected to Participate at the 2022 BMO Healthcare Conference

Oct 4, 2022

Events

Model Medicines Selected to Participate at the 2022 BMO Healthcare Conference

Oct 4, 2022

Events

Model Medicines Selected to Participate at the 2022 BMO Healthcare Conference

Oct 4, 2022

Announcement

Model Medicines Announces Launch of Oncology Programs with Multiple AI-Discovered Compounds Demonstrating Drug-Like Activity for Two High Value, Difficult to Drug, Oncogenic and Epigenetic Targets

Oct 4, 2022

Announcement

Model Medicines Announces Launch of Oncology Programs with Multiple AI-Discovered Compounds Demonstrating Drug-Like Activity for Two High Value, Difficult to Drug, Oncogenic and Epigenetic Targets

Oct 4, 2022

Announcement

Model Medicines Announces Launch of Oncology Programs with Multiple AI-Discovered Compounds Demonstrating Drug-Like Activity for Two High Value, Difficult to Drug, Oncogenic and Epigenetic Targets

Mar 28, 2022

Press

Model Medicines Featured in C&EN's Coverage of Next-Generation COVID-19 Antivirals

Mar 28, 2022

Press

Model Medicines Featured in C&EN's Coverage of Next-Generation COVID-19 Antivirals

Mar 28, 2022

Press

Model Medicines Featured in C&EN's Coverage of Next-Generation COVID-19 Antivirals

Apr 6, 2020

Press

Model Medicines Accepted To Join The Alliance for Artificial Intelligence in Healthcare (AAIH)

Apr 6, 2020

Press

Model Medicines Accepted To Join The Alliance for Artificial Intelligence in Healthcare (AAIH)

Apr 6, 2020

Press

Model Medicines Accepted To Join The Alliance for Artificial Intelligence in Healthcare (AAIH)

Mar 30, 2020

Press

Model Medicines COVID-19 Drug Development Program Highlighted by Catalyst Health 2.0

Mar 30, 2020

Press

Model Medicines COVID-19 Drug Development Program Highlighted by Catalyst Health 2.0

Mar 30, 2020

Press

Model Medicines COVID-19 Drug Development Program Highlighted by Catalyst Health 2.0

Mar 29, 2020

Press

Model Medicines Highlighted as VC Backed StartUp Battling COVID-19 by MedCityNews

Mar 29, 2020

Press

Model Medicines Highlighted as VC Backed StartUp Battling COVID-19 by MedCityNews

Mar 29, 2020

Press

Model Medicines Highlighted as VC Backed StartUp Battling COVID-19 by MedCityNews

Mar 28, 2020

Press

Model Medicines COVID-19 Drug Development Program Highlighted by FreshBrewedTech

Mar 28, 2020

Press

Model Medicines COVID-19 Drug Development Program Highlighted by FreshBrewedTech

Mar 28, 2020

Press

Model Medicines COVID-19 Drug Development Program Highlighted by FreshBrewedTech

Mar 25, 2020

Announcement

Model Medicines Joins The Fight To Battle The Global COVID-19 Pandemic

Mar 25, 2020

Announcement

Model Medicines Joins The Fight To Battle The Global COVID-19 Pandemic

Mar 25, 2020

Announcement

Model Medicines Joins The Fight To Battle The Global COVID-19 Pandemic

Jan 16, 2020

Events

Model Medicines discuss AI Drug Discovery at JPM 2020 Healthcare Week

Jan 16, 2020

Events

Model Medicines discuss AI Drug Discovery at JPM 2020 Healthcare Week

Jan 16, 2020

Events

Model Medicines discuss AI Drug Discovery at JPM 2020 Healthcare Week