Drug Programs

Delivering on the Promise of AI Drug Discovery

Through GALILEO™, we’ve discovered 192 compounds for 26 targets, validated with multiple world class academic and corporate laboratories. Our programs have been validated with the leading academic and corporate research laboratories in the world.

Infectious Diseases

Our infectious disease program is developing the next generation of antivirals that have broader activity and demonstrate best-in-class antiviral characteristics.

1 Lead Preclinical POC

10+ Targets

50+ Assets In Vitro Validation

Oncology

Our Oncology program has discovered potential therapeutics for two broad spectrum oncology targets, AXL/BRD4.

2 Targets

20 Assets In Vitro Validation

Gastrointestinal Motility

Our program is focused on the growing evidence linking gastrointestinal dysmotility to numerous indications including weight disorders and neurological disorders.

1 Target

1 Asset In Vitro Validation

Autoimmune, Inflammation & Rare Diseases

We recently launched a program and completed in-silico discovery work for compounds against multiple targets related to ANCA-Associated Vasculitis (AAV)

ANCA (anti-neutrophil cytoplasmic antibody)-associated vasculitis is a group of rare, life-threatening, immune disorders, which are characterized by a “necrotizing inflammatory process that predominantly affects small and medium-sized blood vessels” such as arterioles, capillaries, and venules.

There are three subtypes of AAV that include Granulomatosis with polyangiitis (GPA, previously Wegener’s disease), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA, previously Churg-Strauss syndrome)

5 Targets

100+ Assets In Silico Discovery

We recognize that no one business can revolutionize the way medicines are discovered and developed on their own. We want to leverage our technology and expertise in partnership with the world’s leading researchers and scientists.

  • A broad spectrum, orally available antiviral therapeutic with an extended half-life and a well documented safety and toxicity profile that can be administered on an outpatient basis is an extreme and urgent unmet medical need, which would be a game-changer in the global fight against COVID-19.

    Adolfo Garcia-Sastre, PhD
    Director of the Global Health and Emerging Pathogens Institute
    Icahn School of Medicine at Mount Sinai

  • As COVID-19 continues to evolve worldwide, we need a multi-pronged approach to control this disease. MDL-001, a potent, oral, safe and well tolerated, direct-acting agent may offer a convenient treatment to prevent disease progression and allow people to resume daily life more quickly.”

    Davey Smith, MD
    Chief of Infectious Diseases and Global Public Health
    UC San Diego Health